LPL and atherosclerosis: In addition to the aforementioned antigens, there are many others associated with atherosclerosis including collagen, fibrinogen, advance glycation-end products (AGE), (LP(a)), lipoprotein-lipase (LPL), and microbial antigens (9) which have not been explored in the context of targeted therapeutics, and so their potential in the generation of either a preventative vaccine or potentially antigen-specific Tregs for uses as therapeutic treatment in atherosclerosis remains unknown.