Therefore, the high densities of mMCP5+ and mMCP6+ MCs in 5CreCAT mice had higher densities of both stromal and intraepithelial mMCP5+ MCs than age matched TS4Cre APClox468 (cAPC) mice that develop polyposis due to loss of function of APC in gut epithelial cells (Supplementary Figure 2). The gene discussed is APC; the disease is polyposis.