Growth-related oncogene α (GRO-α) secretion was induced from a non-detectable level (<31.2 pg/ml) to a detectable level in OA and RA osteoblasts (Figure 2) in only a subset of human osteoblasts from different patients (5/14 RA osteoblast populations for both FFA; 11/20 OA osteoblast populations for palmitic acid, 8/20 OA osteoblast populations for linoleic acid). This evidence concerns the gene CXCL1 and rheumatoid arthritis.