γ1 (leaky-late) genes such as ICP5 (major capsid protein), ICP34.5, gD, and gB are expressed throughout infection, increasing in transcription only a few fold after replication of DNA has commenced while expression of γ2 (true-late) genes such as UL41 (VHS), UL38, UL36, UL20, gC, and gK, does not occur in significant amounts until after replication of DNA (Rybachuk, 2009). Here, PAEP is linked to infection.