KLF9 promotes the expression of peroxisome proliferator-activated receptor γ coactivator 1α (PGC1α), resulting in hepatic gluconeogenesis, and it is involved in glucocorticoid-induced hyperglycemia and diabetes (Cui et al., 2019; Sweet et al., 2019). The gene discussed is PPARGC1A; the disease is Hyperglycemia.