Even though myocarditis and pericarditis are both relatively common cardiac irAEs of ICIs, some studies have implied that they seldom occur at the same time.3 PD‐1/PD‐L1 inhibitors appear to be more prone to myocarditis and pericardial disease than CTLA‐4 inhibitors, while CTLA‐4 inhibitors induce more vasculitis such as temporal arteritis.3, 21 The occurrence of myocarditis induced by PD‐1/PD‐L1 inhibitors may be related to the initial higher dose. The gene discussed is CD274; the disease is myocarditis.