CD8A and neoplasm: In addition, there was an inverse association between the proportion of CD45−B7H4+ cells and CD3+CD8+ T cells in tumor tissues of 26 IDC cases (p < 0.0001), especially in the cases expressing high levels of B7H4 (> 20% CD45−B7H4+ cells in live cell population, 14 cases, p = 0.0006) (Fig. 1b).