FCMD is caused by mutation of the fukutin gene (FKTN)16, which encodes a Golgi-based ribitol phosphate transferase that catalyzes the biosynthesis of tandem ribitol phosphate structures on α-DG by sequential action with fukutin-related protein (FKRP)13. This evidence concerns the gene FKTN and Congenital muscular dystrophy, Fukuyama type.