This analysis indicated that tumor xenografts derived from siNNT-AS1–transfected T24 cells featured lower NNT-AS1 (Figure 7D, P < 0.05) and HMGB1 protein expression (Figure 7E, P < 0.05) as well as higher miR-496 expression (Figure 7F, P < 0.05) compared with the siNC group. The gene discussed is HMGB1; the disease is neoplasm.