Additional analysis (Fig. S3) of several cytokines (Tnf-α, Il-6, IL-1β, and IFN-γ) and antimicrobial factors (Reg3γ, S100a8, and S100a9) found to increase during RIMD infection showed a similar trend, i.e., they were also strongly induced by infection with POR1 or POR2 but not POR3. The gene discussed is S100A8; the disease is infection.