In contrast, when AHR was stably overexpressed in Jurkat T cells by infection with lentivirus-containing AHR-expressing vector pCDH-CMV/AHR (Fig. 3F), AHR-mediated signaling could be detected by the enhanced downstream CYP1A1 gene expression (Fig. 3G), and significantly increased HIV-luc/VSV-G infection was detected by increased luciferase activity and gag mRNA production (unpaired t test, P < 0.001) (Fig. 3H). The gene discussed is CYP1A1; the disease is infection.