Among patients with T2DM, the AUCs increased from 0.60 (95% CI 0.57–0.63) to 0.63 (95% CI 0.59–0.66) and 0.64 (95% CI 0.61–0.67) for BNP and hs-Tnl (DeLong’s test, both P < 0.001), respectively. Here, NPPB is linked to type 2 diabetes mellitus.