SCD and malignant colon neoplasm: After SCD1 transfection for 48 h, the percentage of colon cancer cells in the G2/M phase decreased (LoVo: 13.6%–8.3%; HCT-116: 18.3%–10.4%) compared to the control (Fig. 3c), 1 μM A939572 treatment for 48 h significantly increased the G2/M phase into 22.3% (LoVo) and 24.1% (HCT-116).