RHPN2 and neoplasm: To determine whether in vitro transfer of miR-205 could effectively inhibit endogenous RHPN2 in tumor cells, RT-qPCR and western blot analysis were performed to measure the mRNA and protein expression of RHPN2 in LNCaP cells co-cultured with hBMSCs-miR-205 (Fig. 6c, d).