NPPB and myocardial infarction: This is consistent with a previous report from the Izhevsk family study and the Belfast (UK) component of the PRIME (Prospective Epidemiological Study of Myocardial Infarction) study that showed elevated NT‐proBNP in hazardous drinkers.40 This finding is further supported by increased risk of heart failure among heavy drinking men in the prospective BRHS (British Regional Heart Study).24 However, our study goes further by showing that there is a biomarker dose‐response effect across the 4 categories of heavy drinking at levels of NT‐proBNP that are below clinical thresholds for heart failure.