TGFB1 and Hepatic fibrosis: Our results clearly demonstrated that both C. cainito and C. oliviforme leaf extracts significantly alleviated CCl4-induced oxidative stress and liver damage, as evidenced by histopathological liver fibrosis changes and a marked hepatoprotective effect that are denoted by significant reduction in TGF-β transcription level, as well as significant inhibition in DNA laddering fragmentation.