Patients in Cluster2 were younger (mean age 49.39 vs. 52.30 years old, p = 0.037), had a higher predicted risk for metastasis (84.3% vs. 15.7%, p < 0.0001), higher AFP level (p < 0.0001), bigger tumor size (p = 0.019), and higher proportion of patients with a higher tumor grade (Figure 6B and Table S3). This evidence concerns the gene AFP and neoplasm.