AFP and neoplasm: After controlling for age, gender, AFP, tumor size, and tumor stage in multivariate Cox proportional regression model, Cluster2 patients still had significantly worse OS (p = 0.045, HR: 1.842 with 95% CI (1.012, 3.355)) and RFS (p = 0.041, HR: 1.657 with 95% CI (1.20, 2.692)).