CR1 and Alzheimer disease: Interestingly, recent genetic association studies of AD and other dementias have established correlations between specific risk factors such as ABCA7, CR1, FERMT2, NME8, SLC24A4, SORL1, ZCWPW1, and GALNT7 to CAA, with ABCA7 and CR1 having the strongest association [182], enhancing the necessity of further cellular and molecular studies to dissect this relationship in detail.