Results from cumulative studies have demonstrated that DAs result in reduction in tumour size in 20 to 100% (median 62%), resolution of visual field defects in 33 to 100% (median 67%), resolution of amenorrhea in 40 to 100% (median 78%), resolution of infertility in 10 to 100% (median 53%), improvement of sexual function in 6 to 100% (median 57%), resolution of galactorrhoea in 33 to 100% (median 86%), and normalization of PRL in 40 to 100% (median 68%) of the patients [25]. The gene discussed is PRL; the disease is Infertility.