BIRC5 and ovarian carcinoma: Furthermore, and consistent with the increased proliferative capacity of hCECs that are grown with a feeder layer, knockdown of the genes encoding the transcriptional repressor adipocyte enhancer binding protein 1 (AEBP1) and survivin (BIRC5), and whose expression is also markedly increased in hCECs grown with iHFL or i3T3 (Figure 6C), was recently shown to considerably suppress the proliferation, migration and epithelial-mesenchymal transition of gastric and ovarian cancer cells, respectively [47,48].