On the other hand, a predisposing effect has been suggested to take place in mothers, as giving birth to HLA‐DERAA‐positive children may convey an increased risk of RA for DERAA‐negative mothers.174 In this setting, allogeneic fetal cells containing DERAA have been proposed to evoke an immune response that could be potentially cross‐reactive with DERAA‐containing vinculin. Here, VCL is linked to rheumatoid arthritis.