A large decrease has been reported for the lumbar spine, which is a trabecular bone‐rich site, while a relatively slow decline has been observed for the femoral neck, total hip, and distal one‐third of the radius.114, 115, 116 Furthermore, the effects of discontinuing PTH may depend on the sex.117 Women with osteoporosis may lose a greater portion of their BMD than men with osteoporosis after the cessation of teriparatide. This evidence concerns the gene PTH and osteoporosis.