CD4 and gastric cancer: To further determine the effect of 22 TIICs on the prognosis of GC patients, LASSO and multivariate Cox regression analysis were used to select the seven best survival-related TIICs (CD8 T cells, activated memory CD4 T cells, gamma delta T cells, monocytes, macrophages M2, neutrophils and eosinophils) and develop an immunoscore formula.