S100A4 and neoplasm: Finally, S100A4 level was 1.4 ± 0.8 ng/ml in sera from naïve mice (Fig. 3F, yellow), increased to 15.5 ± 3.7 ng/ml in tumor-bearing mice (p < 1 × 10−6, Fig. 3F, blue), remained high at 16.3 ± 5.1 ng/ml in vehicle-treated mice (p < 1 × 10−6, Fig. 3F, red), dropped to 6.3 ± 2.7 ng/ml in imatinib-treated mice (p < 1 × 10−6, Fig. 3F, brown).