CCL2 and neoplasm: ELISA (data from both cell lines were pooled) showed 0.052 ± 0.030 ng/ml of CCL2 in naïve mice sera (n = 48, Fig. 4E, upper-black), increased to 2.358 ± 0.524 ng/ml in tumor-bearing mice sera (n = 48, p < 1 × 10−6, Fig. 4E, upper-red), remained high at 2.418 ± 0.512 ng/ml in vehicle-treated mice sera (n = 12, p < 1 × 10−6, Fig. 4E, upper-green).