To determine the tumorigenic impact of the PSPC1 and PTK6 interaction in HCC cells, we overexpressed PSPC1 and PTK6 (or PTK6-KM) in SK-hep1 cells (Fig. 1e), which expressed no PSPC1 and a low level of PTK6 (Supplementary Fig. 1h). This evidence concerns the gene PSPC1 and hepatocellular carcinoma.