PSPC1 and neoplasm: Our data showed that PSPC1 and Wnt3a had higher expression (H-score with a discriminatory threshold higher than 200) at late (III and IV) stages compared to early (I and II) stages of HCC tumor tissues, whereas the expression levels of nuclear p-Y523-PSPC1 and nuclear PTK6 were higher at early stages than late stages of HCC tumors (Fig. 5b–e).