ANGPT1 and acute respiratory distress syndrome: Moreover, Mei et al. demonstrated that MSCs transfected with the Ang-1 gene were significantly more effective than MSCs alone in a murine model of LPS-induced ALI, providing additive benefits in both pulmonary vascular permeability and alveolar inflammation, as evaluated by reductions in albumin and pro-inflammatory cytokine levels in BAL, respectively [81].