MACC1 and ovarian serous adenocarcinoma: In three independent TCGA cohort data with total 1680 ovarian serous adenocarcinoma tissue samples, most samples could not detect miR-338-3p alteration, 4 cases detected deep deletions, and only 69 cases detected amplifications, which also showed an expression profile negative related to MACC1 (Fig. 1b,c).