These include RN7SKP237 and ARHGAP19-SLIT, that are up-regulated, and AC003092.1and LOC101928516 that are down-regulated, in CF airway tissues (Fig. 4a); LINC01023 which is down-regulated in CF lung parenchyma tissues (Fig. 4b); and two that are common to CF airway and parenchyma tissues, LINC01558 is up-regulated, and LOC100133050 is down-regulated (Fig. 4c). The gene discussed is ENSG00000223786; the disease is cystic fibrosis.