The LncRNAs which exhibit similar expression trends in CF epithelial cell lines as compared with those observed in the microarray data obtained from CF lung tissues, include RN7SKP237, ARHGAP19-SLIT1, AC003092.1 and LOC101928516 differentially expressed in the CF airway tissues; LINC01023 which is down-regulated in CF lung parenchyma tissues; and LINC01558 and LOC100133050, that exhibit similar expression trend both in the CF airway and parenchyma tissues. This evidence concerns the gene AFDN-DT and cystic fibrosis.