Of the top 10 LncRNAs that are significantly up- or down-regulated in the CF airway tissues, EEF1E1-BLOC1S5 and ARHGAP19-SLIT1 are read through transcripts, uc.363+, uc.8- and uc.476 are ultra-conserved LncRNAs, while the remaining have not been characterized. This evidence concerns the gene BLOC1S5 and cystic fibrosis.