The majority (62%) of newly diagnosed asylum seekers presented with a CD4 count of < 350 cells/μl, and an important minority (22%) with advanced HIV infection (CD4 count < 200 cells/μl) necessitating primary OI prophylaxis, which not only reflects findings from other European studies, but underscores the importance of timely linkage for individual health benefits [20–22]. The gene discussed is CD4; the disease is HIV infectious disease.