In this analysis, the use of the susceptible line Harrington does not significantly impede the infection process of any of the Pgt isolates used, thus, all isolates should be able to release their effectors/elicitor repertoire to manipulate the host which should include avirulence proteins as well as proteins that evolved to suppress R-gene mediated resistance responses, even in the absence of the cognate R-gene. The gene discussed is SLCO2A1; the disease is infection.