IDH1 and central nervous system cancer: The rs10069690 had an association in the same direction for all glioma subtypes (OR = 1.75, 1.31 and 1.24 for IDH-wt, IDH-mutant and 1p/19q intact, and IDH-mutant and 1p/19q co-deleted, respectively), although IDH-mutant and 1p/19q co-deleted was not significant after adjusting for 25×3 tests (p = 0.018).