DDB1 and familial pancreatic carcinoma: By analyzing the publicly assessable data for of PDAC within the Gene Expression Profiling Interactive Analysis (GEPIA) dataset, we found that DDB1 transcription was increased significantly in pancreatic cancer tissues and varied in different stages (Figure 1A,B); high mRNA expression of DDB1 was associated with shorter overall survival (OS) (p = 0.012) but not disease-free survival (DFS) (p = 0.22; Figure 1C).