They are classified as PD‐1 inhibitors and act on the interaction between PD‐L1 expressed on tumor cells and PD‐1 expressed on activated T‐cells, thereby blocking the inhibition of T‐cells and inducing tumor death.22 Therefore, many studies have suggested the possibility of using PD‐L1 expression levels as a predictor of the response to immune checkpoint inhibitors.23, 24. The gene discussed is CD274; the disease is neoplasm.