PCK1 and colorectal carcinoma: We analyzed other publicly available CRC gene expression datasets and consistently observed PCK1 to be significantly upregulated (p=0.01, Student’s t-test; Figure 4E) in CRC liver metastases relative to primary tumors (Figure 4E–G) (Kim et al., 2014; Stange et al., 2010; Ki et al., 2007).