Additional adjustment for sex, diabetes duration, BMI, HDLcholesterol, LDL cholesterol, C-reactive protein, eGFR and a history of smokingmodestly attenuated these inverse associations, with only those of PFHxS [OR = 90,95% confidence interval (CI) = 0.83–0.98] and PFOS (OR = 0.90, 95% CI = 0.82–0.98)remaining significantly associated with stroke. This evidence concerns the gene CRP and stroke disorder.