CEP290 and Leber congenital amaurosis: However, structural defects of cilia as well as differences in ciliary length are correlated with severe developmental diseases.14 Polycystic kidney tissues of foetus have been suffering from MKS3 with mutation in TMEM67 gene showed longer cilia than wild‐type tissues.15 LCA patients with mutations in CEP290 gene never been identified with an increased ciliary length.