Concerning quantification of immunohistochemical antigen expression, the percentage of positive cases for MMP-2 in group A (fibroadenoma) and B (breast cancer) was 15 (41.67%) and 25 (86.11%), respectively (p<0.0009), while the percentage of positive cases for MMP-9 in breast tumor tissues of women from groups A and B was 25 (66.67%) and 28 (93.33%), respectively (p < 0.0138) (Table 2). The gene discussed is MMP9; the disease is breast cancer.