These activated pathways include UPR, protein ubiquitination, oxidative stress response, NF-κB signaling, IL-6 signaling, IL-8 signaling, IL-10 signaling, TGF-β signaling, HGF signaling, cell cycle regulation, EMT regulation, etc. Some of these pathways are related to cancer mechanisms or inflammation. The gene discussed is NFKB1; the disease is cancer.