In AD-like NC/Nga mice, the CS-treated group, after treatment with concanavalin A for 24 h and 48 h, displayed lower production of Th2 cytokines such as IL-4, IL-5, and IL-13, and a chemokine, eotaxin, than the production levels in the control group (Fig. 5). Here, IL13 is linked to Alzheimer disease.