CD8A and neoplasm: Moreover, we conducted flow cytometry with antibodies against IFN-γ and CD8 in these positive samples, and found that the frequency of IFN-γ + and CD8 + TILs among the TILs co-cultured with the autologous tumor cell lines was significantly higher than that in the TILs alone, while the expression of SRSF2 in these TILs was downregulated by siSRSF2 (Fig. 1c–i).