Besides EMT, flawed apoptosis of tumor cells was also one pivotal account for incremental chemo‐resistance of neoplastic cells.33 As illustrated by Figure 3A,B, knockout of MALAT‐1 could significantly attenuate the multiplication capacity of LSCC cell lines, and apoptosis of the LSCC cells was promoted when MALAT1 was silenced (Figure 3C). The gene discussed is MALAT1; the disease is neoplasm.