Plasma TrxR level in CRP group [7.12 (6.08, 8.37) U/mL] was remarkably decreased when compared with TrxR levels in CUP group [10.07 (8.19, 11.02) U/mL] or in GC patients before clinical interventions [9.09 (7.96, 10.45) U/mL], providing a possibility that TrxR level may be a potential indicator to monitor the therapeutic efficiencies of GC patients (Fig. 3B). Here, CRP is linked to gastric cancer.