CXCL9 and CXCL11 were negatively correlated with CD4+ T-cell count at 1-year-infection point (CXCL9, r = − 0.5692, p = 0.0007; CXCL11, r = − 0.3741, p = 0.0349) (Fig. 3e). The gene discussed is CXCL9; the disease is infection.