Mutations in MT-ND6 have been found in association with several diseases, including Leber’s Hereditary Optic Neuropathy (LHON), where retinal ganglion cells are affected leading to loss of visual acuity, and Leigh Syndrome, a primarily neurological condition with paediatric onset [21]. This evidence concerns the gene MT-ND6 and Leber hereditary optic neuropathy.