SSB and infection: We evaluated the significant changes of metabolites and the correlation with the metabolic pathways, while using an enrichment analysis from MetaboloAnalyst 4.0 Software, based on metabolites peak areas from La-WT-infected as compared to La-arg−-infected macrophages (Figure 3, Table S1), La-WT-infected compared to uninfected macrophages (Figure S3, Table S2), and La-arg−-infected macrophages when compared to uninfected macrophages (Figure S4, Table S3) to understand how infection alters macrophage metabolism.