LDHA and gastric carcinoma: All-trans retinoic acid (ATRA), an active metabolite of vitamin A, has shown therapeutic efficacy in modulating CSC subpopulations, evidenced by reductions in the CSC markers CD44 and ALDH in gastric carcinoma models in vitro and in vivo and the attenuation of CSC-like properties in ALDH-high expressing ovarian CSCs [58,59].