ARG1 and neoplasm: Exosome liberated miR-310a-30p is understood to polarize macrophages into an M2 phenotype via the activation of PTEN/P13Kγ signalling, favouring the malignant properties of tumour cells, due in part to the expression of the anti-inflammatory cytokine (IL-10) and arginase-1 (Arg1) [72].