CASP3 and HIV infectious disease: While all tested parameters were at significantly higher levels in AGS-treated HIV-infected cells versus HIV-infected cells, the highest levels of HIV RNA and p24 were detected at day 1 post-infection, with further decrease by day 5 (p < 0.05) (Figure 4A,B) The kinetics of oxidative stress markers, ROS and 4-HNE-adducted protein expression, as well as cleaved caspase-3 were the opposite: we observed their increase from day 1 to day 5 of HIV-infection (p < 0.05).