MUC5AC and metabolic disease: From the microbiota standpoint, apart from the consolidation of healthy-like relative abundances of some bacteria as mentioned above (i.e., Collinsella, Coprococcus and Christensenellaceae) and the obvious increases in the same bacterial genera represented in the probiotic mixture (Bifidobacterium, Lactobacillus and Streptococcus), we also found a significant increase in Akkermansia, a mucin-degrading microbe identified as a promising next-generation candidate for the development of novel food or pharma supplements for metabolic disorders [64].