In particular, increased levels of Collinsella have so far been found in overweight and obese individuals (including pregnant women) as well as in patients suffering from type 2 diabetes and symptomatic atherosclerosis, and are generally associated, albeit with some discordance, with a number of metabolic parameters, including insulin, triglycerides and LDL cholesterol [37,39,59]. The gene discussed is INS; the disease is type 2 diabetes mellitus.