LMNA and Hutchinson-Gilford progeria syndrome: SOCE involves a variety of Ca2+‐dependent signaling pathways and multiple transcription factors associated with muscle growth, differentiation, and remodeling (Stiber & Rosenberg, 2011); therefore, the dysregulated influx of calcium in progerin‐expressing myoblasts may contribute to the maladaptive remodeling of muscle observed in HGPS patients (Merideth et al., 2008).