BMAL1 and neoplasm: Consequently, ETSB could reoriginate molecule clock to reset voided thymic rudiment into endogenous renovation by Clock/Arntl‐Per3/Tim loop re‐priming TECs into MET/EMT dynamic reversion in central microenvironment for thymic progenitors enriched and subjected to systemic innovation toward TCR‐evolving orchestration, with innate‐adaptive defense dynamics revival against progressive biologic burden and tumor challenges.